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| Player | Organization | Year | Position | School |
|---|---|---|---|---|
| Brady Feigl | Los Angeles Angels | 2017 | Pitcher | U of Mississippi |
| Brett Bond | Houston Astros | 2017 | Catcher | U of Missouri |
| Jake Burger | Chicago White Sox | 2017 | Infield | Missouri State |
| Nic Perkins | Washington Nationals | 2017 | Catcher | Drury |
| Tanner Houck | Boston Red Sox | 2017 | Pitcher | U of Missouri |
| Troy Newell | Texas Rangers | 2017 | Pitcher | Jefferson College |
| Brett Graves | Oakland Athletics | 2014 | Pitcher | U of Missouri |
| Tanner Houck | Toronto Blue Jays | 2014 | Pitcher | Collinsville High |
| Calvin Munson | St. Louis Cardinals | 2013 | Pitcher | Francis Howell |
| Dan Tobik | Los Angeles Angels | 2013 | Pitcher | UTM |
| David Masters | Washington Nationals | 2013 | Infield | Central Arizona College |
| Nate Goro | Los Angeles Angels | 2013 | Infield | Jefferson College |
| Ben Turner | San Francisco Giants | 2012 | Catcher | U of Missouri |
| Dan Holst | Cleveland Indians | 2012 | Outfield | Parkway South |
| Shae Simmons | Atlanta Braves | 2012 | Pitcher | Southeast Missouri State |
| Tate Matheny | St. Louis Cardinals | 2012 | Outfield | Westminster |
| Trent Blank | Colorado Rockies | 2012 | Pitcher | Baylor U |
| William Dupont | Toronto Blue Jays | 2012 | Infield | Lafayette |
| Brett Graves | St. Louis Cardinals | 2011 | Pitcher | Francis Howell |
| Charlie Lowell | Florida Marlins | 2011 | Pitcher | Wichita State |
| Conner Mach | New York Yankees | 2011 | Outfield | U of Missouri |
| Dane Gronewald | Atlanta Braves | 2011 | Pitcher | Jefferson College |
| David Masters | Arizona Diamondbacks | 2011 | Infield | Timberland |
| David Schmidt | St. Louis Cardinals | 2011 | Pitcher | CBC |
| Phil McCormick | San Francisco Giants | 2011 | Pitcher | U of Missouri |
| Drew Benes | St. Louis Cardinals | 2010 | Pitcher | Arkansas State |
| Blair Springfield (Fall) | Chicago Cubs | 2009 | Outfield | MacArthur High |
| Dane Opel | Washington Nationals | 2009 | Outfield | Edwardsville High |
| Evan Button | Arizona Diamondbacks | 2009 | Outfield | University of Mississippi |
| Jacob Turner*** | Detroit Tigers | 2009 | Pitcher | Westminster Christian |
| Kyle Mach | San Francisco Giants | 2009 | Infield | University of Missouri |
| Nate Goro | Detroit Tigers | 2009 | Infield | Lafayette High |
| Rob Wort | Washington Nationals | 2009 | Pitcher | Jefferson College |
| Scott Sommerfeld | Cleveland Indians | 2009 | Outfield | Parkway South High |
| Tim Clubb | Chicago Cubs | 2009 | Pitcher | Missouri State University |
| Vince Howard | Atlanta Braves | 2009 | Outfield | Sikeston High |
| Aaron Shafer | Chicago Cubs | 2008 | Pitcher | Witchita State |
| Blake Tekotte | San Diego Padres | 2008 | Outfielder | University of Missouri |
| Casey Moore | Detroit Tigers | 2008 | Catcher | Saint Louis University |
| Charlie Lowell | Texas Rangers | 2008 | Pitcher | Winfield |
| Chris Hick | Houston Astros | 2008 | Pitcher | Georgia Tech |
| David Phelps | New York Yankees | 2008 | Pitcher | Notre Dame |
| Derrick Phillips | Washington Nationals | 2008 | Outfielder | Westminster |
| Jacob Priday | Houston Astros | 2008 | Outfielder | University of Missouri |
| John Hellweg | Anaheim Angels | 2008 | Pitcher | Florida CC |
| Matt Frevert | St. Louis Cardinals | 2008 | Pitcher | Missouri State |
| Tim Clubb | Tampa Bay Rays | 2008 | Pitcher | Missouri State |
| Brock Bond | San Francisco Giants | 2007 | Infielder | University of Missouri |
| Drew Benes | Cincinnati Reds | 2007 | Infielder | Westminster |
| Evan Frey | Arizona Diamonbacks | 2007 | Outfielder | University of Missouri |
| John Hellweg | Florida Marlins | 2007 | Pitcher | St. Dominic |
| Nick Schmidt*** | San Diego Padres | 2007 | Pitcher | University of Arkansas |
| Ross Detwiler*** | Washington Nationals | 2007 | Pitcher | Missouri State University |
| Sean Loggins | Anaheim Angels | 2007 | Catcher | McCluer North |
| Chris Nash | Cleveland Indians | 2006 | Infielder | Marquette |
| Devon Collis | Colorado Rockies | 2006 | Pitcher | University of Arkansas |
| John Wilson | L.A. Dodgers | 2006 | Infielder | St. Charles |
| Kent Gerst | Chicago White Sox | 2006 | Outfielder | Ft. Zumwalt West |
| Max Scherzer*** | Arizona Diamonbacks | 2006 | Pitcher | University of Missouri |
| Mike Pontius | Cleveland Indians | 2006 | Pitcher | Wentzville/Holt |
| Nathan Culp | San Diego Padres | 2006 | Pitcher | University of Missouri |
| Travis Mitchell | St. Louis Cardinals | 2006 | Outfielder | Parkway Central |
| Aaron Shafer | Cleveland Indians | 2005 | Pitcher | Troy |
| Adam Hall | Tampa Bay Rays | 2005 | Pitcher | Pacific |
| Chris Frey | Colorado Rockies | 2005 | Outfielder | Highland/U. of Arizona |
| Chris Nash | Los Angeles Angels | 2005 | Infielder | Marquette |
| Jesse Barr | New York Yankees | 2005 | Pitcher | McCluer/Mo. Baptist |
| Joe Muich | New York Yankees | 2005 | Catcher | DeSmet/Wichita State |
| Joe Simokatis | Chicago Cubs | 2005 | Infielder | St. Mary's/University of Nebraska |
| Josh Alley | San Diego Padres | 2005 | Outfielder | Anna Jonesboro/U. of Tennessee |
| Mike Phelps | Chicago Cubs | 2005 | Pitcher | Hazelwood W./Central Mo. State |
| Sam LeCure | Cincinnati Reds | 2005 | Pitcher | Jeff City Helias/U. of Texas |
| Sean Toler | Colorado Rockies | 2005 | Pitcher | Parkway West |
| Blake Dewitt*** | L.A. Dodgers | 2004 | Infielder | Sikeston |
| Lucas Harrell | Chicago White Sox | 2004 | Pitcher | Ozark |
| Scott Elbert*** | L.A. Dodgers | 2004 | Pitcher | Seneca |
| Todd Stein | Arizona Diamondbacks | 2004 | LHP | |
| Adam Jahnsen | St. Louis Cardinals | 2003 | Pacific/Xavier | |
| Andy Sides | New York Mets | 2003 | Pitcher | DeSoto |
| Lucas May | L.A. Dodgers | 2003 | Infielder | Parkway West |
| Max Scherzer | Philadelphia Phillies | 2003 | Pitcher | Parkway Central |
| Sal Fersella | St. Louis Cardinals | 2003 | Outfielder | Vianney/SIU-C |
| Shaun Marcum | Toronto Blue Jays | 2003 | Missouri State University | |
| Kyle McClellan | St. Louis Cardinals | 2002 | Pitcher | Hazelwood West |
| Ronnie Ray | Anaheim Angels | 2002 | Pitcher | Pacific |
| Sam LeCure | Philadelphia Phillies | 2002 | Pitcher | Jeff City Helias |
| Wes Jaillet | St. Louis Cardinals | 2002 | Pitcher | Lafayette/SLU |
| Dan Shouse | St. Louis Cardinals | 2001 | Pitcher | Marquette/SLU |
| Jonathon Estes | St. Louis Cardinals | 2001 | Pitcher | Ritenour |
| Matt Roguse | Arizona Diamondbacks | 2001 | Pitcher | |
| Bob Keppel*** | New York Mets | 2000 | Pitcher | DeSmet |
| Don Rogers | Colorado Rockies | 2000 | Infielder | DeSmet |
| Garrett Bauer | Texas Rangers | 2000 | Pitcher | Lafayette |
| J.R. Warner | California Angels | 2000 | Outfielder | Priory/Mizzou |
| Peter Stonard | New York Yankees | 2000 | Infielder | Clayton |
| Robert Mosby | Kansas City Royals | 2000 | Pitcher | East St. Louis |
| Ken Lutz | Cincinnati Reds | 1999 | Collinsville |